Oio Lab Turns Towards Longevity

Oio Lab is turning toward longevity with the launch of their new NAD Face Serum and a science driven ritual for smart aging.

This July, with the launch of our latest Hero product, we invite you to explore a new philosophy of skincare — one that doesn’t chase youth, but activates your skin’s potential to look and function at its best, for longer.

Founded in Poland by former lawyer and ingredient researcher Joanna Ryglewicz, Oio Lab is quietly redefining what modern skincare can be. Each formula is developed in-house by a team of certified chemists, blending cutting-edge biotechnology with high-performance botanicals in a way that feels both rigorous and intentional.

This month’s Discovery is a celebration of skin longevity — and what it means to feel vital, vibrant, and supported at every age.

At the heart of this philosophy is a quiet but significant shift.

“I’ve never fully resonated with the term ‘anti-ageing’—even though I’ve used it. It never quite fit. With INTERCELLULAR NAD Face Serum, I wanted to shift the focus: how can we support the skin in maintaining its peak condition for longer? How do we preserve our best skin — not just for today, but for at least another decade?”
— Joanna Ryglewicz, Founder of Oio Lab

Smart aging is about working with the skin — not against it. It means supporting its natural ability to repair, regenerate, and stay resilient. It’s rooted in epigenetics, cellular energy, and the science of long-term renewal. And it reflects a deeper cultural shift — away from “perfection,” and toward authenticity and activated potential.

Meet our Hero product: INTERCELLULAR Longevity Facial Serum

INTERCELLULAR isn’t a quick fix. It’s a future-facing formula rooted in the science of cellular energy, epigenetic repair, and the skin’s natural rhythm. Our NAD Face Serum has been developed over three years inside Oio Lab’s in-house laboratory, this milky-textured serum was created to help skin function — and feel — at its peak.

At the center of the formula is RejuveNAD™, a patented extract of organic sunflower sprouts, cultivated in a controlled indoor system for exceptional efficacy. This botanical active targets one of the deepest causes of skin ageing: the steady decline of NAD⁺, a molecule essential for cellular energy, DNA repair, and regeneration.

Rather than delivering NAD⁺ directly — which is notoriously unstable — RejuveNAD™ takes a smarter approach. It works by activating NAMPT, the enzyme responsible for recycling and replenishing NAD⁺ inside the cell. In doing so, it supports mitochondrial vitality, DNA repair, and reduces the presence of “zombie cells” — senescent cells that accumulate with age and interfere with renewal.

This mechanism has been studied extensively — and the results are compelling:

It boosts NAD⁺ synthesis by 111% by activating NAMPT — the essential enzyme that powers cellular renewal, yet naturally declines with age.
It amplifies cellular energy by 84% in aged skin, helping cells “breathe” better, repair faster, and regain their natural rhythm.
It helped skin appear up to 8.2 years younger, visibly improving firmness, smoothness, and facial definition in just six weeks of twice-daily use.

Think of it as recharging your skin’s battery. Not forcing it into youth, but restoring its ability to thrive.

Formula Synergy: More Than a Single Active

While RejuveNAD™ leads the way, INTERCELLULAR was never designed to work alone. Skin longevity is complex — so this formula is built as a system. Each ingredient supports a different aspect of skin vitality: hydration, renewal, structure, and protection.

A key supporting player is spermidine — a rising star in longevity science. Naturally present in the body, spermidine is known for its role in supporting autophagy, the skin’s built-in detox and repair process that declines with age. By encouraging cellular renewal from within, spermidine helps improve skin density, elasticity, and resilience over time.

In INTERCELLULAR, it’s delivered via a vegan collagen complex sourced from microalgae, chosen for its high bioavailability and ability to deeply penetrate the skin.
This core is supported by:

Pomegranate seed stem cells, to brighten and protect against oxidative stress
Ultra-pure ozonated omega 3, 6, and 9 esters, exclusive to Oio Lab, to nourish the skin barrier and enhance absorption
Ectoine, a fermented molecule that helps defend against environmental stress and soothe sensitive skin

Each ingredient plays a purposeful role in helping the skin stay balanced and intelligently supported — for the long game.

But what sets this serum apart is not just what it does—it’s how it feels. The texture is soft, milky, and intelligent. It sinks in immediately and supports your beauty rituals.

The Perfect Pairing: O-MEGA MILK Cleansing Milk & Mask

Soft and deeply hydrating, O-MEGA MILK is a versatile two-in-one formula that cleanses without stripping and doubles as a replenishing mask when your skin needs a pause.

Inside, a harmony of nutrient-rich plant butters and oils — apricot, cherry, grape seed, passion seed, and shea — is paired with pea protein surfactants and Oio Lab’s exclusive ozonated omega 3, 6, and 9 esters, known for their antibacterial and antifungal properties. The result is a formula that soothes without smothering, and purifies without disrupting the skin’s natural balance.

Used as a mask, it’s clinically shown to increase hydration by 70% within 30 minutes, and reduce visible redness by 31% just 15 minutes after application.

A gentle multitasker, made for moments of reset.

A Ritual That Feels Like a Reset

This month’s Discovery isn’t just skincare — it’s a daily ritual of regeneration. A gentle return to what your skin already knows: how to restore, how to renew, how to hold itself with strength and softness.

It reflects a quiet shift in how we define beauty — less about perfection, more about potential.
Less about reversing time, and more about moving with it.
Intelligently. Intuitively. On your own terms.